Detalhe da pesquisa
1.
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 603(7900): 328-334, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197632
2.
Publisher Correction: A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Nature
; 604(7905): E13, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332336
3.
Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model.
Bioorg Med Chem Lett
; 30(23): 127625, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33096160
4.
Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors - Lead optimization - Part III.
Bioorg Med Chem Lett
; 29(3): 491-495, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553737
5.
Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.
Bioorg Med Chem Lett
; 27(20): 4730-4734, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947155
6.
Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II.
Bioorg Med Chem Lett
; 27(20): 4735-4740, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927793
7.
PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.
Blood
; 124(11): 1777-89, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25006129
8.
Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.
Nat Commun
; 14(1): 3719, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349337
9.
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Sci Transl Med
; 13(610): eabc7804, 2021 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516826
10.
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models.
Mol Cancer Ther
; 20(2): 250-262, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33310762
11.
Pan-TGFß inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade.
Oncoimmunology
; 9(1): 1811605, 2020 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33224628
12.
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer.
J Med Chem
; 63(2): 512-528, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31721572
13.
Oncogenic dependency on ß-catenin in liver cancer cell lines correlates with pathway activation.
Oncotarget
; 8(70): 114526-114539, 2017 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29383099
14.
Concomitant Inhibition of PI3Kß and BRAF or MEK in PTEN-Deficient/BRAF-Mutant Melanoma Treatment: Preclinical Assessment of SAR260301 Oral PI3Kß-Selective Inhibitor.
Mol Cancer Ther
; 15(7): 1460-71, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27196754
15.
Information processing in bacterial chemotaxis.
Sci STKE
; 2002(132): pe25, 2002 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12011495
16.
Use of carboxylated cellulose nanofibrils-filled magnetic chitosan hydrogel beads as adsorbents for Pb(II).
Carbohydr Polym
; 101: 75-82, 2014 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24299751
17.
SAR103168: a tyrosine kinase inhibitor with therapeutic potential in myeloid leukemias.
Leuk Lymphoma
; 54(7): 1488-99, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23121564
18.
Receptor methylation controls the magnitude of stimulus-response coupling in bacterial chemotaxis.
J Biol Chem
; 277(39): 36760-5, 2002 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119291
19.
Organization of the receptor-kinase signaling array that regulates Escherichia coli chemotaxis.
J Biol Chem
; 277(39): 36748-54, 2002 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119289
20.
Interactions between Escherichia coli nucleoside-diphosphate kinase and DNA.
J Biol Chem
; 277(7): 5163-7, 2002 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11742005